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Gender-affirming endocrine care of transgender people
ISSM University. T Sjoen G. Mar 2, 2018; 208285 Disclosure(s): Is included in the presentation
Prof. Dr. Guy T Sjoen
Prof. Dr. Guy T Sjoen
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1. Principles of gender-affirming hormone treatment in transgender persons.
2. Knowledge of effects and side-effects of gender-affirming hormone treatment
3. Fertility options for transgender persons
Gender affirming hormonal treatment is desired by many transgender persons to help them successfully live as a member of their identified gender. The mental health professionals (psychiatrists and/or psychologists), by preference working in a multidisciplinary Gender team, may guide to make an informed decision about hormonal treatment. The goal of treatment in transgender men is to induce virilization and to stop menses. The prinicipal hormone treatment is a testosterone preparation. In transgender women oestrogen and anti-androgen treatment is provided. Treatment regimens are currently not standardised and include various forms of oestrogens, progestins, and/or (anti-) androgens as reported by different clinical centres. So far, no randomized intervention trials are available so treatment remains largely experience-based. Options for fertility preservation should be discussed before hormonal intervention. Short-, mid- and long-term outcome data are quite reassuring.
Appropriate care for transgender persons will lead to better outcome and should avoid unnecessary psychological pain, health risks (e.g. secondary psychiatric conditions or suicide), or self medication with inherent greater risk of complications.
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Mueller SC, De Cuypere G, T'Sjoen G. Transgender Research in the 21st Century: A Selective Critical Review From a Neurocognitive Perspective. Am J Psychiatry 2017:appiajp201717060626

Coleman E, Bockting W, Botzer M, Cohen-Kettenis P, DeCuypere G, Feldman J, Fraser L, Green J, Knudson G, Meyer WJ, Monstrey S, Adler RK, Brown GR, Devor AH, Ehrbar R, Ettner R, Eyler E, Garofalo R, Karasic DH, Lev AI, Mayer G, Meyer-Bahlburg H, Hall BP, Pfaefflin F, Rachlin K, Robinson B, Schechter LS, Tangpricha V, van Trotsenburg M, Vitale A, Winter S, Whittle S, Wylie KR, Zucker K. Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People, Version 7. International Journal of Transgenderism 2012; 13:165-232
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